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Image Search Results
Journal: Biomedicines
Article Title: Neutralization of Marinobufagenin Demonstrates Efficacy In Vitro and In Vivo in Models of Pre-Eclampsia.
doi: 10.3390/biomedicines13040782
Figure Lengend Snippet: Figure 4. (A) MBG-induced decreased expression of VEGF was attenuated by pretreatment with H3L2 (4 µg/mL) (* p < 0.05). (B) MBG-induced decreased expression of PlGF was attenuated by pretreatment with H3L2 (4 µg/mL) (* p < 0.05). (C) MBG-induced increased expression of sFlt-1 was attenuated by pretreatment with H3L2 (4 µg/mL) (* p < 0.05). (D) MBG-induced increased expression of sEng was attenuated by pretreatment with H3L2 (4 µg/mL) (* p < 0.05).
Article Snippet: Measurement of angiogenic factors: Levels of the pro-angiogenic factors VEGF and PlGF, and the anti-angiogenic factors sFlt-1 and sEng, were measured with commercially available kits (Human VEGF Quantikine ELISA Kit (DVE00);
Techniques: Expressing
Journal: International Journal of Molecular Sciences
Article Title: Combined Therapy Versus Fortified Anti-VEGF Monotherapy in Type C Polypoidal Choroidal Vasculopathy: Long-Term Outcomes and Exploratory Biomarker Insights
doi: 10.3390/ijms27031224
Figure Lengend Snippet: Various vascular markers for type C PCV, CSCR, and nvAMD. Before intravitreous injection (IVI), aqueous protein levels of VEGF/PlGF/HIF-1α/β-catenin/Wnt1 were detected using ELISA on patients with AMD, PCV, or CSCR. In ( A ), the PCV ( n = 17) or nvAMD ( n = 41; control) levels of VEGF were median [Q1, Q3]: 106.19 [80.00, 203.81] or 191.91 [116.68, 289.96]. In ( B ), the PCV ( n = 13) or nvAMD ( n = 29) levels of PlGF were median [Q1, Q3]: 1.39 [0.72, 18.45] or 15.48 [11.25, 17.90]. The PCV/CSCR/nvAMD (pre-IVI; n = 9/4/16) levels of β-catenin ( C ) were 983.77 ± 329.68/1224.33 ± 743.69/3622.41 ± 499.70. The PCV/CSCR/nvAMD (pre-IVI; n = 5/4/20) levels of HIF-1α ( D ) were median [Q1, Q3]: 6096.66/8705.06/1091.28 [5173.83/5939.04/803.69, 7811.37/14,239.77/3210.46]. Additionally, the PCV/CSCR (pre-IVI) levels of Wnt1 ( E ) were 1180.66 ± 172.41 ( n = 6)/1387.12 ± 289.54 ( n = 4). Significance was * p < 0.05.
Article Snippet: Protein levels in aqueous humor were quantified using commercial ELISA kits [ , ]: VEGF (BMS227/2, Bender MedSystems, Wien, Austria),
Techniques: Injection, Enzyme-linked Immunosorbent Assay, Control